Direct maxacalcitol injection into hyperplastic parathyroids improves skeletal changes in secondary hyperparathyroidism
نویسندگان
چکیده
منابع مشابه
Skeletal findings in secondary hyperparathyroidism
Figure 1: (a) X-ray of the hands showing bilateral acro-osteolysis with resorption of the distal phalangeal tufts (arrows). (b) X-ray of the skull showing abnormal bony mineralization along the patient’s calvarium. (c) X-ray of the right shoulder showing resorption of the distal end of the clavicle and also mild focal subchondral cystic change along the posterior lateral humeral head, better vi...
متن کاملCellular changes following direct vitamin D injection into the uraemia-induced hyperplastic parathyroid gland
Background. Hyperplasia of the parathyroid gland (PTG) is associated not only with excessive secretion of parathyroid hormone (PTH) but also with changes in the parathyroid cell (PTC) characteristics (i.e. hyperproliferative activity and low contents of vitamin D and calcium-sensing receptors). The control of PTG hyperplasia is most important in the management of secondary hyperparathyroidism (...
متن کاملRelationship between parathyroid gland size and responsiveness to maxacalcitol therapy in patients with secondary hyperparathyroidism.
BACKGROUND Although vitamin D has been reported to be useful in the treatment of patients with secondary hyperparathyroidism, it is not effective in some of them. The goal of this study was to see whether a relationship could be found between maxacalcitol responsiveness and parathyroid gland size. METHODS Parathyroid gland size was measured by ultrasonography in 25 patients with secondary hyp...
متن کاملEfficacy of direct injection of calcitriol into the parathyroid glands in uraemic patients with moderate to severe secondary hyperparathyroidism.
INTRODUCTION Secondary hyperparathyroidism (2HPT) is a common complication in uraemic patients. When medical therapy, including high doses of intravenous calcitriol, fails to suppress the pathological secretion of parathyroid hormone (PTH), one of the newly developed interventional techniques, such as percutaneous ethanol injection therapy (PEIT), is an option before taking the surgical solutio...
متن کاملPercutaneous calcitriol injection therapy (PCIT) for secondary hyperparathyroidism: multicentre trial.
A multicentre trial of percutaneous calcitriol injection therapy (PCIT) was designed to evaluate its clinical usefulness. During a 12-week period, measurement of intact PTH concentration, and other parameters, and ultrasonography were carried out in conjunction with PCIT in 19 haemodialysis patients with secondary hyperparathyroidism and enlarged parathyroid glands (PTGs) that were resistant to...
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ژورنال
عنوان ژورنال: Kidney International
سال: 2006
ISSN: 0085-2538
DOI: 10.1038/sj.ki.5001564